asw

 


Komentar

Posting Komentar

Postingan populer dari blog ini

Meninjau Teknik Diagnosis KesalahanSensor dan Kontrol Toleransi Kesalahanpada Baterai Lithium-Ion KendaraanListrik

  Pendahuluan Perkembangan   kendaraan   listrik  (Electric Vehicle/EV)  semakin   pesat   seiring   meningkatnya   kesadaran   akan pentingnya   energi   bersih  dan  ramah   lingkungan . Di  balik kemajuan   tersebut ,  baterai  lithium-ion  menjadi   komponen kunci  yang  menentukan   kinerja  dan  keselamatan   kendaraan . Salah  satu   faktor   penting   dalam   menjaga   performa   baterai adalah   sistem  sensor yang  bertugas   mengawasi   berbagai parameter  seperti   tegangan ,  arus , dan  suhu . Sensor  bertindak   sebagai   indra   bagi  Battery Management System (BMS)  dalam   memantau   kondisi   baterai   secara  real-time.  Apabila  sensor  mengalami   kesalahan   atau   kega...
Baca selengkapnya

MXene in Sensor Applications: Types, Progress, and Prospects

  Abstract The emerging two-dimensional (2D) material, MXene, has attracted widespread attention from researchers across various disciplines due to its unique properties. In the field of sensors, MXene exhibits exceptional conductivity, a high specific surface area, and excellent hydrophilicity, making it an ideal platform for biosensor recognition elements. Additionally, its surface is rich in functional groups, allowing for versatile modifications tailored to specific application needs. The 2D planar structure of MXene offers advantages superior to those of bulk nanomaterials, making it highly suitable for the development of high-performance sensors. This review discusses the latest advancements in MXene-based sensors, including stress-strain sensors, optical sensors, temperature sensors, humidity sensors, and biological signal marker sensors. The preparation methods, performance characteristics, and sensing mechanisms of each type are comprehensively reviewed. Furthermore, this ...
Baca selengkapnya

In-line Fiber Optic Sensor for Real-time Detection of IgG Aggregates in Affinity Chromatography

Abstract: Therapeutic monoclonal antibodies (mAbs), particularly Immunoglobulin G (IgG), are extensively used in treating a variety of diseases. However, their production often faces significant challenges, primarily due to aggregation during the manufacturing process. This aggregation negatively impacts the safety and quality of the product, making the detection and removal of aggregates critical. Chromatography plays a key role in mAb purification, but conventional systems lack efficient real-time monitoring for both the product and its aggregates. This study introduces a novel in-line fiber-optic sensor based on localized surface plasmon resonance (LSPR) to detect IgG and its aggregates during affinity chromatography. The sensor, placed at the outlet of a Protein A column, detects IgG aggregates at concentrations below 1%, with a sensitivity capable of distinguishing differences as small as 0.3% between samples. The slower dissociation rates of aggregates, compared to monomers, allo...
Baca selengkapnya